Population pharmacokinetics of polymyxin b
WebOct 1, 2024 · However, the correlation between polymyxin B pharmacokinetics (PK) and creatinine clearance (CrCL) is poor. This study aimed to develop a population PK model of … Web× Close. The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such …
Population pharmacokinetics of polymyxin b
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WebFeb 1, 2024 · Background. Polymyxin B (PMB) is a basic cyclic polypeptide antibiotic produced by Bacillus polymyxa, and is one of the last options for treating multi-drug-resistant negative bacterial infections in clinical practice.In recent years, many population pharmacokinetic studies of PMB have been conducted. WebNov 18, 2024 · Polymyxin B is the last line of defense in treating multidrug-resistant gram-negative bacterial infections. Dosing of polymyxin B is currently based on total body weight, and a substantial intersubject variability has been reported. We evaluated the performance of different population pharmacokinetic models to predict polymyxin B exposures …
WebAug 4, 2024 · The individual PK parameters estimated from the population analysis for polymyxin B, including the steady-state minimum concentration ... Population … Web8. Sandri, Ana M., et al. "Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens." Clinical infectious diseases 57.4 (2013): 524531. - 9. Sandri, Ana M., et al. "Pharmacokinetics of polymyxin B in patients on continuous venovenous haemodialysis." Journal of
WebApr 13, 2024 · Ozoralizumab (OZR), a tumor necrosis factor alpha (TNFα) inhibitor, is a NANOBODY® compound that binds to TNFα and human serum albumin. The main … WebJun 18, 2024 · The population PK was determined using NONMEM and Monte Carlo simulation was performed to evaluate the exposures of different dosing regimens. Results. The PK analyses included 342 steady-state concentrations and a two-compartment model was optimal for polymyxin B PK data modelling.
WebJul 1, 2024 · Population pharmacokinetics and limited sampling strategy for therapeutic drug monitoring of polymyxin B in Chinese patients with multidrug-resistant Gram …
WebMar 29, 2024 · Bjerre LM, Ramsay T, Cahir C, Ryan C, Halil R, Farrell B, Thavorn K, Catley C, Hawken S, Gillespie U, Manuel DG. Assessing potentially inappropriate prescribing (PIP) and predicting patient outcomes in Ontario's older population: a population-based cohort study applying subsets of the STOPP/START and Beers' criteria in large health administrative … grand sunpia hachinoheWebAug 1, 2024 · Polymyxin B is served as a last-line agent for Carbapenem-resistant organisms (CRO) infections. This study aimed to establish a population pharmacokinetic … chinese restaurant sandy bay tasmaniaWebFeb 1, 2024 · Wang P, Zhang Q, Zhu Z, et al. Population Pharmacokinetics and Limited Sampling Strategy for Therapeutic Drug Monitoring of Polymyxin B in Chinese Patients … grand sunlife hotel alanyaWebMar 29, 2024 · Keywords: polymyxin B, critically ill patients, population pharmacokinetics, albumin levels, dosing optimization Citation: Liang D, Liang Z, Deng G, Cen A, Luo D, Zhang … chinese restaurants amherst ohioWebVoriconazole (VRC) is used as first line antifungal agent against invasive aspergillosis. Model-based approaches might optimize VRC therapy. This study aimed to investigate the predictive performance of pharmacokinetic models of VRC without pharmacogenetic information for their suitability for model-informed precision dosing. Seven PopPK models … chinese restaurants anchorage alaskaWebSandri AM, Landersdorfer CB, Jacob J, et al. Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens. Clin … chinese restaurants anderson inWebNov 15, 2024 · The aim of this study was to assess polymyxin B pharmacokinetics (PK) in patients with varying degrees of renal dysfunction and in patients who require ... (2024) … chinese restaurants andover ma